- Country: USA
- Summary: A Human Multi-Organ Tissue Equivalent Platform to Model High Consequence Threat Agents
- UST Ref No: 116731910
- Deadline: 14 Apr 2025
- Financier: Self Financed
- Purchaser Ownership: Government
- Tender Value: Refer Document
- Notice Type: Tender
- Document Ref. No.: HT942525R0053
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- Description:
- Description
The United States Army Medical Research Acquisition Activity (USAMRAA) intends to issue a Firm Fixed Price sole source contract under the authority of FAR 6.302-1 (a) (2) - Only One Responsible Source and No Other Services will Satisfy Agency Requirements to Wake Forest Institute for Regenerative Medicine (WFIRM), Winston-Salem, NC, on behalf of the United States Army Medical Research of Infectious Diseases (USAMRIID).
The Government has a requirement for the development of a micro engineered human organ/tissue equivalent platform for modeling the pathogenic outcomes of emerging infectious diseases and test the efficacy of medical countermeasures (MCMs). The scope of effort will encompass the task of protecting the warfighter from a natural or manmade attack and have the ability to rapidly identify the best methods available to maintain mission critical status. The Contractor will conduct all activities in compliance with FDA CVM regulations, current Good Manufacturing Processes (cGMP), and other applicable regulations as necessary. The Government seeks an Organ Tissue Equivalent (OTE) platform, which utilizes cutting edge 3D organ-on-a-chip technologies and offers one such solution for the military by providing a tool for rapidly identifying medical countermeasures for the prevention and treatment of emerging viral diseases. The lung OTE shall be comprised entirely of human cells including the epithelial, endothelial, stromal, and inflammatory components of native lung tissue. Unlike typical 2D systems, these constructs shall be arranged in a pseudostratified architecture and produce mucus and surfactant providing a physiologically relevant model system. The overarching goal of the proposed studies is to validate the human lung construct as a flexible model for viral pulmonary infections and the resultant inflammatory response. The system will also be used to test the efficacy of potential medical countermeasures, and for identifying potential d... - Documents:
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CLICK HERE TO LOGINA Human Multi-Organ Tissue Equivalent Platform to Model High Consequence Threat Agents - USA Tender
The DEPT OF DEFENSE | DEFENSE HEALTH AGENCY (DHA), a Government sector organization in USA, has announced a new tender for A Human Multi-Organ Tissue Equivalent Platform to Model High Consequence Threat Agents. This tender is published on USARFP under UST Ref No: 116731910 and is categorized as a Tender. Interested and eligible suppliers are invited to participate by reviewing the tender documents and submitting their bids before the deadline on 2025-04-14.
The estimated tender value is Refer Document, and full details, including technical specifications and submission requirements, are provided in the official tender documents. Ensure all submissions meet the criteria outlined to be considered for evaluation.
