Tender Details

Country: USA
Summary: Antibacterial Compound Optimization_Noi
UST Ref No: 84951273
Deadline: 11 Jul 2023
Financier: Self Financed
Purchaser Ownership: Government
Tender Value: Refer Document
Notice Type: Tender
Document Ref. No.: PANMRA-23-P-0000_004865
Purchaser's Detail:
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Description:
Description
THIS IS A NOTICE OF INTENT TO AWARD A SOLE-SOURCE CONTRACT AND IS NOT A REQUEST FOR COMPETITIVE PROPOSALS.
The U.S. Army Medical Research Acquisition Activity (USAMRAA) intends to award a sole source basis in accordance FAR 6.302-1 with George Mason University (GMU), Fairfax, VA. as the only responsible source that can provide specialized and optimized antibacterial compounds, in support of the Bacterial Disease Branch (BDB) at Walter Reed Institute of Research (WRAIR) located in Silver Spring MD. This acquisition is being conducted under FAR Part 15.
Objectives
The contractor shall synthesize proprietary antibacterial compounds (CT-AP1) for delivery to WRAIR.
The contractor shall synthesize optimized antibacterial compounds for delivery to WRAIR.

Specific Tasks / Requirements
The contractor shall synthesize proprietary antibacterial compounds (CT-AP1) for delivery to WRAIR for testing in in vitro assays and x-ray crystallography experiments.
The contractor shall perform multiple rounds of synthetic synthesis of novel/optimized
antibacterials within 2-4 months. The contractor shall synthesize the antibacterial compounds, using structural data and structure-activity relationship data employing their knowledge of chemistry, organic chemistry, medicinal chemistry, and associated laboratory techniques and skills.
The contractor shall deliver the optimized synthesized compounds to WRAIR within 1-4 weeks after receiving data from WRAIR.
The contractor shall provide a monthly progress report including data and results on relevant tasks performed
WRAIR will conduct assay tests including enzyme inhibition, biofilm inhibition and minimum inhibitory concentration (MIC) assays.
Assay data will be sent back to contractor and process will repeat until MIC of 1µg/mL is achieved.
All compounds shall be shipped to WRAIR with a certificate of analysis indicating at least 95% purity and at least 10mg quan...
Documents:

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Antibacterial Compound Optimization_Noi - USA Tender

The DEPT OF DEFENSE, a Government sector organization in USA, has announced a new tender for Antibacterial Compound Optimization_Noi. This tender is published on USARFP under UST Ref No: 84951273 and is categorized as a Tender. Interested and eligible suppliers are invited to participate by reviewing the tender documents and submitting their bids before the deadline on 2023-07-11.

The estimated tender value is Refer Document, and full details, including technical specifications and submission requirements, are provided in the official tender documents. Ensure all submissions meet the criteria outlined to be considered for evaluation.