- Country: USA
- Summary: Antibody Expression Service
- UST Ref No: 103226643
- Deadline: 05 Jul 2024
- Financier: Self Financed
- Purchaser Ownership: Government
- Tender Value: Refer Document
- Notice Type: Tender
- Document Ref. No.: NOI-NIAID-24-2227934
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- Description:
- Description
This is a Notice of Intent, not a request for proposal. The National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH) intends to negotiate on an other than full and open competition basis with Biointron Biological USA, Inc. for antibody expression service.
The Laboratory of Viral Diseases (LVD) within the National Institute of Allergy and Infectious Diseases (NIAID) carries out investigations into the molecular biology of viruses, the
interactions of viruses with host cells, the pathogenesis of viral diseases, and host defense mechanisms. These studies are designed to increase fundamental knowledge and facilitate the development of new approaches to the prevention of treatment of disease. Since the COVID-19 pandemic began early in 2020, LVD, and particularly the Cell Biology Section (CBS) has devoted a good portion of our work to study the human coronaviruses. The goals of the Laboratory of Viral Diseases (LVD) are to determine the mechanisms used by viruses to infect cells, express, and replicate their genomes, assemble infectious particles, and evade the host immune response. Basic information obtained from these studies is used to design antiviral agents and live and subunit recombinant vaccines.
The purpose of this contract is to provide purified custom antibodies, expressed in cell culture. These antibodies will be directed against influenza A hemagglutinin, SARS-CoV-2 spike and other protein variants, also against other proteins to be decided at a later date. Expressed custom antibodies are very useful in the lab for probing viral proteins, generation of immunity, etc. The LVD uses these antibodies to test neutralization of virus, measure affinity and avidity of binding to viral proteins by ELISA and BLI assays. LVD also determine the effects of antibody maturation on the above measurements.
The statutory authority for this sole source requirement is 41 U.S.C. 1901 (a) (1) as implem... - Documents:
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CLICK HERE TO LOGINAntibody Expression Service - USA Tender
The HEALTH AND HUMAN SERVICES, DEPARTMENT OF, a Government sector organization in USA, has announced a new tender for Antibody Expression Service. This tender is published on USARFP under UST Ref No: 103226643 and is categorized as a Tender. Interested and eligible suppliers are invited to participate by reviewing the tender documents and submitting their bids before the deadline on 2024-07-05.
The estimated tender value is Refer Document, and full details, including technical specifications and submission requirements, are provided in the official tender documents. Ensure all submissions meet the criteria outlined to be considered for evaluation.
