Tender Details

Country: USA
Summary: CRISPR activation (CRISPRa) and knockout (CRISPRko) libraries
UST Ref No: 124704820
Deadline: 25 Aug 2025
Financier: Self Financed
Purchaser Ownership: Government
Tender Value: Refer Document
Notice Type: Tender
Document Ref. No.: 75N94025Q00190
Purchaser's Detail:
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Description:
Description
This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation, and a separate written solicitation will not be issued. This solicitation number is 75N94025Q00190 and is issued as a Request for Quotation (RFQ). The solicitation/contract will include all applicable provisions and clauses in effect through Federal Acquisition Circular 2025-05. The North American Industry Classification (NAICS) Code is 541380 and the business size standard is $19m. However, this solicitation is not set aside for total small business. This acquisition is being conducted using Simplified Acquisition Procedures in accordance with FAR Part 13. Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) intends to contract on a sole source basis with Horizon Discover Bioscience to procure the following custom reagents/kits.1. LP_193551 SLC CRISPRa, CRISPRmod CRISPRa Human Synthetic sgRNA - SMARTpool 0.1 nmol, 452 wells, 2 plates, plate type Echo 384, Horizontal - Qty (1) EA2. LP_193555 CRISPRKO, Edit-R Human Synthetic sgRNA pool 0.1 nmol, 455 wells, 2 plates, plate type Echo 384, Horizontal - Qty (1) EAThis procurement supports an ongoing research project focused on identifying novel phosphate transporters through genome wide functional genomic screens. The study design requires the use of both CRISPR activation (CRISPRa) and knockout (CRISPRko) libraries optimized for use in human cells, with pooled lentiviral delivery formats suitable for high-throughput screening. To maintain scientific integrity and ensure valid data comparability, the libraries must: • Include genome-wide coverage targeting nearly all human protein-coding genes. • Contain multiple validated sgRNAs per gene for both CRISPRa and CRISPRko modalities. • Be delivered in a pooled lentiviral format compatible with ...
Documents:

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CRISPR activation (CRISPRa) and knockout (CRISPRko) libraries - USA Tender

The HEALTH AND HUMAN SERVICES, DEPARTMENT OF | NATIONAL INSTITUTES OF HEALTH, a Government sector organization in USA, has announced a new tender for CRISPR activation (CRISPRa) and knockout (CRISPRko) libraries. This tender is published on USARFP under UST Ref No: 124704820 and is categorized as a Tender. Interested and eligible suppliers are invited to participate by reviewing the tender documents and submitting their bids before the deadline on 2025-08-25.

The estimated tender value is Refer Document, and full details, including technical specifications and submission requirements, are provided in the official tender documents. Ensure all submissions meet the criteria outlined to be considered for evaluation.