- Country: USA
- Summary: Light-Sheet Microscope for 3D High-Resolution Imaging of Large Biological Samples
- UST Ref No: 71363390
- Deadline: 13 Sep 2022
- Financier: Self Financed
- Purchaser Ownership: Government
- Tender Value: Refer Document
- Notice Type: Tender
- Document Ref. No.: 75N95022Q00032
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- Description:
- Description
The purpose of this requirement is to purchase a light-sheet microscope system for 3D high-resolution imaging of large biological samples. The microscope will be used to analyze fluorescently labeled elements (e.g., neural activity markers such as Fos and cell-type markers) in whole rat and mouse brains that were altered by drug experience. The use of a light-sheet microscope is to visualize fluorescently labeled elements, such as activity markers and cell type markers, in the whole brain in one image scan. This allows for rapid acquisition of labeling in all brain areas in an unbiased manner, which is important for: (a) identification of brain regions and (b) identification (through correlational analysis) of combinations of brain regions or circuits, that were not previously considered in mediating a behavior of interest. For this to be effective, the microscope:
Requirement (1) must be able to image multiple whole rat and mouse brains in a single imaging session. Requirement (2) is ease of use by non-expert users, such as minimal number of adjustments and manual steps to use for imaging, and a lower probability of damage to machine. Requirement (3) is the ability to run these brains in batch mode so the microscope can be run at all times, which will greatly increase throughput of the microscope that will be in demand for many experiments by different researchers. Requirement (4) is responsiveness of tech support, which has been a severe problem in the past. Requirement (5) is to obtain optically flat images with minimal shadowing to minimize post-processing times. Requirement (6) is for high sensitivity camera acquisition to (a) minimize scan times but (b) more importantly to use lower excitation light intensities to minimize photobleaching of sample brains. Requirement (7) is for automated sample stage and imaging objectives to scan the same samples at multiple resolutions in a single imaging session. The appropriate microscope that fulfills... - Documents:
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CLICK HERE TO LOGINLight-Sheet Microscope for 3D High-Resolution Imaging of Large Biological Samples - USA Tender
The HEALTH AND HUMAN SERVICES, DEPARTMENT OF, a Government sector organization in USA, has announced a new tender for Light-Sheet Microscope for 3D High-Resolution Imaging of Large Biological Samples. This tender is published on USARFP under UST Ref No: 71363390 and is categorized as a Tender. Interested and eligible suppliers are invited to participate by reviewing the tender documents and submitting their bids before the deadline on 2022-09-13.
The estimated tender value is Refer Document, and full details, including technical specifications and submission requirements, are provided in the official tender documents. Ensure all submissions meet the criteria outlined to be considered for evaluation.
