- Country: USA
- Summary: National Institute of Environmental Health Sciences (NIEHS) Assessment of Immunotoxicity - In Vitro and In Vivo Assessment of Immune Function
- UST Ref No: 111917001
- Deadline: 16 Jan 2025
- Financier: Self Financed
- Purchaser Ownership: Government
- Tender Value: Refer Document
- Notice Type: Tender
- Document Ref. No.: 75N96025R00001
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- Description:
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Pre-solicitation Notice - 75N96025R00001
National Institute of Environmental Health Sciences (NIEHS) Assessment of Immunotoxicity - In Vitro and In Vivo Assessment of Immune Function
This notice announces the intended release of solicitation number 75N96025R00001.
DESCRIPTION
This pre-solicitation notice follows a Sources Sought notice that was released on July 26, 2023, under notice number mmunotox_RFI_SSN_NIEHS_2023.
The acquisition will support and assist the National Institute of Environmental Health Sciences (NIEHS) by providing all services and supplies necessary to conduct research studies to evaluate the potential for test agents selected by the Division of Translational Toxicology (DTT) to modulate immune function using established in vitro and in vivo models.
With the increasing awareness of the need for translational toxicology and to reduce the use of animals, the use of in vitro methods to assess immune function will be the focus of DTT-s research efforts to assess altered immunity. The focus of this requirement will be to provide DTT with a mechanism to evaluate chemical induced immunotoxicity by determining: 1) whether chemical or therapeutic agents can modulate the immune response using a battery of in vitro tests to measure immune suppression or stimulation in response to relevant antigens; 2) whether chemical agents have the potential to induce allergic responses using in chemico and in vitro OECD guideline test methods for skin sensitization as part of an integrated panel of tests and; 3) evaluate the potential of a test agent to modulate the immune system using a comprehensive in vivo immune testing panel that evaluates the major components of the immune system in the developing rat and/or adult mice or rats. In addition, because immunology is a developing science, it is expected that new and improved methodology will be required to maintain "state of the art" evaluation. As an additiona... - Documents:
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CLICK HERE TO LOGINNational Institute of Environmental Health Sciences (NIEHS) Assessment of Immunotoxicity - In Vitro and In Vivo Assessment of Immune Function - USA Tender
The HEALTH AND HUMAN SERVICES, DEPARTMENT OF | NATIONAL INSTITUTES OF HEALTH, a Government sector organization in USA, has announced a new tender for National Institute of Environmental Health Sciences (NIEHS) Assessment of Immunotoxicity - In Vitro and In Vivo Assessment of Immune Function. This tender is published on USARFP under UST Ref No: 111917001 and is categorized as a Tender. Interested and eligible suppliers are invited to participate by reviewing the tender documents and submitting their bids before the deadline on 2025-01-16.
The estimated tender value is Refer Document, and full details, including technical specifications and submission requirements, are provided in the official tender documents. Ensure all submissions meet the criteria outlined to be considered for evaluation.
