- Country: USA
- Summary: Notice of Intent to Sole Source - 10X Genomics
- UST Ref No: 125272484
- Deadline: 10 Sep 2025
- Financier: Self Financed
- Purchaser Ownership: Government
- Tender Value: Refer Document
- Notice Type: Tender
- Document Ref. No.: NOI-CC-25-008681
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- Description:
- Description
This is a notice of intent, not a request for a quotation. A solicitation document will not be issued and quotations will not be requested.
This procurement is for 10X Genomics 5- v3 single cell sequencing kits, TCR amplification kits, and Single Cell Multiome ATAC + Gene Expression kits. The kits are composed of reagents for the isolation and amplification of uniquely barcoded ribonucleic acid (RNA) and chromatin accessible regions from individual cells. The 10X Genomics single cell sequencing of immune cells enables high-throughput simultaneous and accurate determination of the nature of an immune response to an infection (what the cells are doing and which cells are doing it). The 10X Genomics platform uses microfluidics to separate individual cells into an emulsion with single gel beads and labels the RNA from each cell with a unique barcode for partitioning into libraries for sequencing. The single cell sequencing kit is proprietary to 10X Genomics, the original equipment manufacturer of the 10X Genomics platform.
These supplies will be used for a study of the immune response to Pneumocystis infection in mouse animal models, as well as studying histone modifications, to better under the Pneumocystis biology. Animals will be infected with the fungal pathogen using a co-housing exposure model, and then followed up overtime, collecting lung tissue samples which will be used to assess changes in gene expression overtime. Single cell sequencing will allow for the profiling of immune cell subsets and B cell receptor sequences during infection, and gene expression changes in the fungal pathogen.
10X Genomics is the sole manufacturer of the 10X Genomics platform and single cell sequencing reagents. Other manufacturer-s single cell single reagents are not compatible for use with the 10x Genomics platform. The Critical Care Medicine Department has independently modified and validated the recommended protocols provided by the 10X Genomics. Any... - Documents:
JOFOC-Under-the-SAT-GlideScope-2025.docx
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CLICK HERE TO LOGINNotice of Intent to Sole Source - 10X Genomics - USA Tender
The HEALTH AND HUMAN SERVICES, DEPARTMENT OF | NATIONAL INSTITUTES OF HEALTH, a Government sector organization in USA, has announced a new tender for Notice of Intent to Sole Source - 10X Genomics. This tender is published on USARFP under UST Ref No: 125272484 and is categorized as a Tender. Interested and eligible suppliers are invited to participate by reviewing the tender documents and submitting their bids before the deadline on 2025-09-10.
The estimated tender value is Refer Document, and full details, including technical specifications and submission requirements, are provided in the official tender documents. Ensure all submissions meet the criteria outlined to be considered for evaluation.
