- Country: USA
- Summary: RNA sequencing and data processing of nasal epithelium samples from never-smoking women in Guatemala
- UST Ref No: 123799801
- Deadline: 16 Aug 2025
- Financier: Self Financed
- Purchaser Ownership: Government
- Tender Value: Refer Document
- Notice Type: Tender
- Document Ref. No.: 25-021812
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- Description:
- Description
This is a notice of intent, not a request for a quotation. A solicitation document will not be issued, and quotations are not being requested.
The National Cancer Institute (NCI) intends to award a firm-fixed price purchase order to the Trustees of Boston University (UEI FBYMGMHW4X95) on a sole source basis for RNA sequencing and data processing of nasal epithelium samples from never-smoking women in Guatemala. The anticipated award date is August 31, 2025.
Boston University developed a protocol to noninvasively collect and preserve samples from the nasal airways and mouth, has successfully analyzed whole genome mRNA expression array in these types of samples, and has shown that mRNA expression patterns in these types of tissue are similar to what is observed in lung tissue. Boston University is at the forefront of this field and has numerous publications evaluating the associations between gene expression and pulmonary effects using nasal swabs as surrogate tissue.
Boston University has applied this methodology for the NCI to the analysis of nasal swabs collected from populations exposed to other air exposures that affect the lung, including tobacco, diesel exhaust, coal combustion. It is critical that samples from this smoky wood study are analyzed in the same laboratory to ensure scientific comparability of the results from previous contracts NCI has to this laboratory (Boston University) that analyzed diesel exhaust, coal combustion, nano particles, and e-waste (Contract #s HHSN261201700630P, HHSN261201300432P, 75N91022P00843). Importantly, these studies of different chemical exposures using the same mRNA expression and laboratory provide an opportunity to compare patterns of mRNA expression in this study of smoky wood with findings from other mRNA studies of other air pollution sources and constituents (diesel engine exhaust, Drizik E, et al. 2020; smoky coal combustion, Wang TW et al. 2015) that the Government is conducting in paral... - Documents:
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CLICK HERE TO LOGINRNA sequencing and data processing of nasal epithelium samples from never-smoking women in Guatemala - USA Tender
The HEALTH AND HUMAN SERVICES, DEPARTMENT OF | NATIONAL INSTITUTES OF HEALTH, a Government sector organization in USA, has announced a new tender for RNA sequencing and data processing of nasal epithelium samples from never-smoking women in Guatemala. This tender is published on USARFP under UST Ref No: 123799801 and is categorized as a Tender. Interested and eligible suppliers are invited to participate by reviewing the tender documents and submitting their bids before the deadline on 2025-08-16.
The estimated tender value is Refer Document, and full details, including technical specifications and submission requirements, are provided in the official tender documents. Ensure all submissions meet the criteria outlined to be considered for evaluation.
