Tender Details

Country: USA
Summary: Role Of T-Cells In Hiv Cns Reservoir Seeding, Persistence, And Neuropathogenesis (R01 Clinical Trial Not Allowed)
UST Ref No: 110536428
Deadline: 18 Mar 2025
Financier: Self Financed
Purchaser Ownership: Government
Tender Value: Refer Document
Notice Type: Tender
Document Ref. No.: RFA-MH-26-110
Purchaser's Detail:
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Description:
Eradicating Latent Reservoirs Of Hiv-1 Within The Body And Achieving A Sterilizing Or Functional Cure Have Become Priority Areas In The Aids Field And Nih Aids Programs Across Many Institutes And Centers, Including Nimh. In Addition Understanding The Mechanisms Of Hiv- Associated Co-Morbidities In The Setting Of Effective Anti-Retroviral Therapy (Art) Is A Major Topic Of Interest In The Field. Hiv Associated Cns (Central Nervous System) Co-Morbidities Continue To Exist Despite Excellent Virologic Control In This Compartment. Hiv Persistence And Neuroinflammation Also Continues To Observed In The Cns In The Setting Of Art. Hiv Targets The Cns Early In Infection, And Hiv-Infected Individuals Suffer From Mild Forms Of Neurological Impairments Even Under Antiretroviral Therapy (Art). Cd4+ T Cells And Monocytes Mediate Hiv Entry Into The Brain And Constitute A Source For Hiv Persistence And Neuronal Damage. Cd8+ T Cells Are Also Massively Recruited In The Cns In Acute Infection To Control Viral Replication.
Documents:

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Role Of T-Cells In Hiv Cns Reservoir Seeding, Persistence, And Neuropathogenesis (R01 Clinical Trial Not Allowed) - USA Tender

The NATIONAL INSTITUTES OF HEALTH, a Government sector organization in USA, has announced a new tender for Role Of T-Cells In Hiv Cns Reservoir Seeding, Persistence, And Neuropathogenesis (R01 Clinical Trial Not Allowed). This tender is published on USARFP under UST Ref No: 110536428 and is categorized as a Tender. Interested and eligible suppliers are invited to participate by reviewing the tender documents and submitting their bids before the deadline on 2025-03-18.

The estimated tender value is Refer Document, and full details, including technical specifications and submission requirements, are provided in the official tender documents. Ensure all submissions meet the criteria outlined to be considered for evaluation.